基于电子健康记录的鼻癌专用大数据平台的构建和应用
Ze-Kai Chen1, Xiao-Qing Wang1, Lin-Lin Xiao1
1Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
American journal of otolaryngology
|January 5, 2024
概括
使用电子健康记录创建了一个针对鼻癌 (NPC) 的新大数据平台. 这种高质量的平台支持现实研究,提高了NPC的研究效率和成果.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 大数据分析大数据分析
背景情况:
- 鼻癌 (NPC) 研究需要强大的数据支持.
- 电子健康记录 (EHR) 包含有价值的患者信息,但通常是碎片化的.
- 建立一个统一的数据平台对于推进NPC研究至关重要.
研究的目的:
- 为鼻癌 (NPC) 开发一个专门的大数据平台.
- 为了利用EHR数据对NPC进行全面的现实研究.
- 为NPC提供数据驱动的洞察力提供基础.
主要方法:
- 一个多学科团队设计了NPC数据元素标准 (14个模块,640个字段).
- 从15个EHR系统中提取和整合了1999年后诊断的患者的数据.
- 采用机器学习和NLP进行数据清理,结构化和标准化,并进行质量控制和加密.
主要成果:
- 该平台包括11,617名NPC患者 (70.83%是男性),平均年龄为48岁.
- 验证了人口统计,实验室和生命体征数据的高完整性和准确性.
- 目前支持六个关于风险因素,诊断,治疗和毒性的研究项目.
结论:
- 通过使用集成的EHR数据,成功建立了一个高质量的NPC专用大数据平台.
- 该平台提高了NPC现实世界的研究效率,成本效益和结果质量.
- 预计未来的多中心数据共享将为NPC产生高质量的现实世界证据.
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