染色体结合蛋白HMGN1通过调节3基因组3的酸化来促进HBVccDNA的转录和复制

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Updated: Jul 6, 2025

Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System
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Identifying Inhibitors of the HBx-DDB1 Interaction Using a Split Luciferase Assay System

Published on: December 21, 2019

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Tan Ming1, Liu Yuting2, Dong Meiling3

  • 1Chongqing Key Laboratory of Child Infection and Immunity, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Department of Infectious Diseases, The Children's Hospital of Chongqing Medical University, Chongqing Medical University Chongqing, China; The Key Laboratory of Molecular Biology of Infectious Diseases Designated by the Chinese Ministry of Education, Chongqing Medical University, Chongqing, China.

Antiviral research
|January 5, 2024
PubMed
概括

高流动性核细胞组结合域1 (HMGN1) 通过结合ccDNA促进乙型肝炎病毒 (HBV) 的转录和复制. 沉默HMGN1抑制HBV复制,提供了一个潜在的治疗策略.

关键词:
在 CLK2 中使用.在HMGN1中.基因组合物 基因组合物cccDNADNA 在线阅读

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