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Updated: Jul 6, 2025

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在PARP9/DTX3L和PARP14中的KH类域协调蛋白-蛋白相互作用以促进癌细胞生存

Hadil Saleh1, Triantafillos Liloglou2, Daniel J Rigden3

  • 1University of Liverpool, Department of Molecular and Clinical Cancer Medicine, 6 West Derby St, Liverpool L7 8TX, UK.

Journal of molecular biology
|January 5, 2024
PubMed
概括

PARP9-DTX3L-PARP14蛋白质复合体通过相互作用,而不是酶活性,促进头支状细胞癌 (HNSCC) 的癌细胞存活. 这种相互作用对于HNSCC.的支持生存信号至关重要.

关键词:
在ADP-ribosylation过程中.阿尔法2折2是什么意思一个宏观的PARP.蛋白质蛋白质相互作用规范表达的表达方式.

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