基于SPR和MMI的纤维传感器,用于同时测量胆固醇度和温度
Wanlu Zheng1, Bo Han2, Ya-Nan Zhang3
1College of Information Science and Engineering, Northeastern University, Shenyang, 110819, China.
Analytica chimica acta
|January 5, 2024
概括
这项研究介绍了一种新的光纤传感器,用于同时测量胆固醇和温度. 该传感器利用表面等离子共振和多模式干扰效应,在生物医学应用中提供高灵敏度和精度.
科学领域:
- 光电学是指光电子产品.
- 生物医学传感传感器
- 纳米材料是一种纳米材料.
背景情况:
- 精确的胆固醇监测对于心血管健康至关重要.
- 现有的传感器往往受到交叉灵敏度和有限的精度的影响.
- 生物样本分析需要同时测量温度.
研究的目的:
- 开发一种双参数光纤传感器,用于同时检测胆固醇和温度.
- 为了提高传感器的灵敏度和选择性,使用表面等离子体共振 (SPR) 和多模干扰 (MMI) 效应.
- 为了解决温度和胆固醇测量之间的交叉敏感性的挑战.
主要方法:
- 使用多模纤维 (MMF) -Au薄膜涂层空心纤维 (HCF) -MMF结构制造一个内纤维传感器.
- 用Au纳米粒子/β-环极 (AuNPs/β-CD) 复合物涂覆HCF,通过SPR检测胆固醇.
- 将糖氨酸纳入HCF以通过MMI传感温度,从而实现双参数测量.
主要成果:
- 传感器显示SPR的波长偏移为12.7nm,MMI的波长偏移为7.9nm,胆固醇度从0到500nm的变化.
- 在30°C-46°C范围内观察到温度敏感度为-0.9nm/°C (SPR) 和2.64nm/°C (MMI).
- 该传感器在检测血清环境中的胆固醇方面表现出卓越的稳定性,选择性和可重复性.
结论:
- 设计的纤维传感器成功地实现了同时和灵敏地测量胆固醇度和温度.
- SPR和MMI效应的结合,以及AuNPs/β-CD和甘油,为双参数传感提供了一个强大的平台.
- 这种传感器在生物医学诊断和健康监测方面具有很大的应用潜力.
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Start by practicing proper hand hygiene to prevent the spread of microorganisms.
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Step 1:
Start by practicing proper hand hygiene to prevent the spread of microorganisms.
Step 2:
Take the thermometer out of the charging unit, switch it on, and wait for the ready sign.
Step 3:
Gently slide the probe cover until a click is heard. This simple action prevents cross-contamination and ensures the correct placement of the probe cover.
Step 4:
Instruct the patient to open their mouth and place...
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