在诊断胸部疾病时使用EBUS引导的冷活检
V Poletti1, S Petrarulo2, S Piciucchi3
1Department of Medical Specialities-Pulmonology, GB Morgagni Hospital, Bologna University-Forlì-Ravenna Campus, Forlì, Italy; Department of Medical and Surgical Sciences (DIMEC), Bologna University, Bologna, Italy; Department of Respiratory Diseases & Allergy, Aarhus University, Aarhus, Denmark.
Pulmonology
|January 5, 2024
概括
与EBUS-transbronchial needle aspiration (TBNA) 相比,胸内疾病的诊断产量优于胸内超声波 - 胸内超声波 - 胸内超声波 - 中间胸内冷藏活检 (EBUS-TMC). 特别有效的EBUS-TMC用于诊断罕见的中关节疾病,并促进高级分析.
科学领域:
- 肺部病理学 肺部病理学
- 胸部外科手术 胸部外科手术
- 诊断成像 诊断成像 诊断成像
背景情况:
- 胸内超声检查 (EBUS) 对于诊断胸内疾病,特别是肺癌的分期至关重要.
- 对于良性和罕见疾病,EBUS的诊断效用需要进一步研究.
研究的目的:
- 为了比较EBUS-transbronchial中冷活检 (EBUS-TMC) 与EBUS-transbronchial针吸收 (TBNA) 的诊断产量和安全性.
- 为了在广泛的胸内疾病中评估这些技术.
主要方法:
- 这是一项追溯观察性研究,涉及48名患者.
- 在2021年8月至2023年10月期间,患者在同一过程中接受了EBUS-TBNA和EBUS-TMC.
主要成果:
- 在EBUS-TMC中,整体诊断收益率 (95.8%) 比EBUS-TBNA (54.1%) 高.
- 埃布斯-TMC在诊断肉类发病,罕见的中关节疾病,超增多性淋巴腺病和淋巴增殖性疾病方面表现出色.
- EBUS-TMC样本更容易接受下一代测序 (NGS) 和免疫组织化学分析.
结论:
- EBUS-TMC增强了中病的精确诊断和亚型,包括淋巴瘤和罕见瘤.
- 这种技术可以减少非诊断程序的发生率.
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