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Updated: Jul 6, 2025

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分泌的IgM调节B细胞中的IL-10表达.

Shannon Eileen McGettigan1, Lazaro Emilio Aira1, Gaurav Kumar2

  • 1Department of Microbiology and Immunology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107, USA.

Nature communications
|January 5, 2024
PubMed
概括

分泌的IgM (sIgM) 限制了IL-10产生的B细胞的扩张. 缺少sIgM会导致这些调节性B细胞的数量增加十倍,从而影响免疫平衡.

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