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Updated: Jul 6, 2025

Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay
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Visualization and Quantification of TGFβ/BMP/SMAD Signaling under Different Fluid Shear Stress Conditions using Proximity-Ligation-Assay

Published on: September 14, 2021

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凯文-1/卡维林-1相互作用通过干扰BMPR2/卡维林-1结合,减弱了肺高血压中BMP/Smad信号传递

Shinya Tomita1, Naohiko Nakanishi2, Takehiro Ogata1,3

  • 1Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, 602-8566, Japan.

Communications biology
|January 5, 2024
PubMed
概括

凯文-1/卡维林-1相互作用抑制了BMP/Smad信号传输,这是肺动脉高血压 (PAH) 的关键途径. 针对这种相互作用,为PAH提供了潜在的新治疗策略.

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