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Updated: Jul 6, 2025

A Seminiferous Tubule Squash Technique for the Cytological Analysis of Spermatogenesis Using the Mouse Model
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Published on: February 6, 2018

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线粒体蛋白酶PARL是精子生成所需的

Sarah Schumacher1, Laura Klose2, Jessica Lambertz2

  • 1Institute of Neuroanatomy, Medical Faculty, University of Bonn, 53115, Bonn, Germany. s.schumacher@uni-bonn.de.

Communications biology
|January 5, 2024
PubMed
概括

线粒体蛋白酶PARL的缺乏会阻止男性半径变化I的进展. 这会损害复杂IV,ATP和的合成,影响男性生育能力.

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Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
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