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Updated: Jul 6, 2025

Measurement of Protein Turnover Rates in Senescent and Non-Dividing Cultured Cells with Metabolic Labeling and Mass Spectrometry
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Published on: April 6, 2022

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在衰老的哺乳动物大脑中,蛋白质循环减缓

Nalini R Rao1, Arun Upadhyay1, Jeffrey N Savas2

  • 1Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Molecular systems biology
|January 5, 2024
PubMed
概括

衰老会破坏细胞蛋白质的循环,特别是在大脑中,有性别特异的模式. 这项研究揭示了与蛋白质循环减少相关的蛋白质酶活性与年龄相关的变化.

关键词:
衰老的衰老 衰老的衰老蛋白质酶体蛋白质组是什么蛋白质营业额的变化定量化的蛋白质组学.稳定同位素标记的标签

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