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循环金属复合物通过PI3K/mTOR/Nrf2信号通路克服了西斯普拉丁的耐药性

Lanmei Chen1,2,3, Wenzhu Yu1,2,3, Hong Tang1,2,3

  • 1Key Laboratory of Computer-Aided Drug Design of Dongguan City, Guangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Dongguan, Guangdong 523808, P. R. China.

Metallomics : integrated biometal science
|January 6, 2024
PubMed
概括

新型复合物在克服非小细胞肺癌 (NSCLC) 中的西斯普拉丁耐药性方面表现有希望. 这些化合物抑制细胞增殖和耐药性机制,提供一种潜在的新型低毒性治疗.

关键词:
A549 / DDPDP 没有在PI3K/mTOR/Nrf2中.耐药性 抗性 抗性 抗性 抗性循环金属化复合物 循环金属化复合物

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