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Updated: Jul 6, 2025
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Oral Health Assessment by Lay Personnel for Older Adults
Published on: February 2, 2020
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在老年印度癌症患者中,潜在不合适药物的评估工具的性能
Sharath Kumar1, Renita Castelino1, Abhijith Rao2
1Department of Clinical Pharmacology, Advanced Centre for Treatment, Research and Education in Cancer, Tata Memorial Centre, Navi Mumbai, India.
Cancer medicine
|January 6, 2024
概括
欧盟的PIM清单显示,对于在老年人中识别潜在不合适药物 (PIMs) 达成的最高一致性. 该工具提供了一种可靠的方法来评估老年人群中PIM的使用情况.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 多药和潜在不适当的药物 (PIM) 使用是老年人面临的重大挑战.
- 确保安全的处方实践对于这一群体至关重要.
- 现有的PIM识别工具有时会产生相互矛盾的结果.
研究的目的:
- 评估和比较五种不同工具的一致性,用于识别老年人潜在不合适的药物 (PIM).
- 确定在老年瘤学人群中进行PIM评估的最可靠工具.
主要方法:
- 对467名60岁及以上的患者进行了回顾性分析.
- 使用了五种PIM识别工具:Beer's-2015,STOPP/START标准v2,PRISCUS-2010,FORTA-2018以及欧盟的PIM列表-2015.
- 布兰德-阿尔特曼图表评估了每个工具与参考标准 (中位数SPV) 之间的一致性,后勤回归分析了PIM使用关联.
主要成果:
- 欧盟(7) -PIM清单显示了与参考标准的最高一致性 (偏差估计=0.010,95%CI: -0.001到0.022).
- 其他工具的偏差置信区间较宽,表明一致性较低.
- 多药性与较高的PIM使用有显著的关联 (OR = 1.47,p < 0.001).
结论:
- 欧盟PIM清单是识别老年人潜在不合适药物 (PIM) 的最可靠工具,因为它具有最少的偏见.
- 这一发现支持使用欧盟的PIM清单来提高老年患者的药物安全性.
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