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Updated: Jul 6, 2025

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
06:35

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

Published on: December 22, 2020

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烯介导的细胞骨功能障碍重塑与癌症相关的纤维细胞,以增强抗瘤免疫治疗

Bing Shi1, Xue Lou1, Feiyan Ma1

  • 1Laboratory for NanoMedical Photonics, School of Basic Medical Science, Henan University, Zhengzhou, Henan, 475001, P. R. China.

Advanced healthcare materials
|January 6, 2024
PubMed
概括

这项研究引入了一种新型烯衍生物 (PDIC-OC),通过诱导细胞亡和抑制TGF-β来重编程与癌症相关的纤维细胞 (CAF). 这种方法有效地打击免疫抑制性瘤微环境,并增强抗瘤免疫力.

关键词:
与癌症相关的纤维细胞.细胞骨功能障碍的发生.免疫疗法 免疫疗法在这种情况下,烯也会产生烯.反应性氧物种 (ROS) 是一种反应性氧物种.

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