尼森袖子胃切除术对中期巴雷特食道回归的有效性
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Pierre Brinas1, Saadeddine Joumaa2, Andrew Currie3
1Bariatric Surgery Unit, University Hospital of Rangueil, 1 Av. du Professeur Jean Poulhès, 31400, Toulouse, France. pierre.brinas@gmail.com.
Obesity surgery
|January 6, 2024
概括
尼森袖子胃切除术 (NSG) 在两年内在约三分之二的患者中显示出治疗巴雷特食道 (BE) 的前景. 这种减肥手术似乎还可以预防新的BE病例,为一种常见的并发症提供了潜在的解决方案.
科学领域:
- 腹部外科 腹部外科
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
背景情况:
- 袖子胃切除术是一种常见的减肥手术,胃食道逆流症 (GERD) 是主要并发症.
- 经过袖子胃切除术后的GERD可以导致巴雷特食道 (BE),这是食道腺癌的前体.
- 与传统方法相比,尼森袖子胃切除术 (NSG) 已证明降低了GERD发病率.
研究的目的:
- 评估尼森袖胃切除术 (NSG) 对巴雷特食道 (BE) 发病率和缓解的长期影响.
主要方法:
- 这是一项双中心的回顾性研究,对692名在2013年9月至2021年7月期间接受NSG的患者进行了研究.
- 手术前和后续上部肠道内镜在手术后1-2年和3-5年.
- 通过活检系统确认BE.
主要成果:
- 在692名患者中有54名 (7.8%) 的组织学证实了BE.
- 在38名已知B.E.患者中,在2年内进行了随访,25名 (64.1%) 患者的B.E.愈合.
- 在2年内对234名随访内镜检查的患者没有观察到新的病例 (de novo BE).
结论:
- 在2年的随访期间,NSG与大约三分之二的患者在现有BE的愈合有关.
- 观察到的BE愈合与NSG的已知GERD减轻益处一致.
- 在减肥手术后,NSG可能为患有或有BE风险的患者提供有利的结果.
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