大气环境和儿科喘的持续性:基于人口的队列研究
Hwan Soo Kim1, Kyunghoon Kim2, Eun Hee Rhee3,4
1Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Asian Pacific journal of allergy and immunology
|January 6, 2024
概括
儿童喘通常会消失,但有些孩子在成年后会出现持续的症状. 诸如入学时年龄较小,男性性别,空气污染暴露和食物过敏等因素增加了喘持久性风险.
科学领域:
- 儿科过敏和免疫学
- 环境健康 环境健康
- 流行病学 流行病学
背景情况:
- 儿童的喘是异质的,很大一部分在成年时经历了症状的消失.
- 然而,将儿童喘轨迹与成人结果联系起来的数据仍然有限.
研究的目的:
- 为了确定与儿童喘在三年随访期间的持续性相关的因素.
- 为了全面分析,将韩国儿童喘研究 (KAS) 的数据与国家医疗保险索赔 (HIRA) 联系起来.
主要方法:
- 对450名青春期前儿童 (7-10岁) 的分析,分为喘缓解或喘持久组.
- 基线临床特征和空气污染物的暴露 (PM2.5,PM10) 的比较.
- 喘持久性根据医疗保健利用和药物处方在入学后三年内定义.
主要成果:
- 较低的入学年龄,男性性别,接近空气污染设施,较高的PM2.5水平和被诊断出食物过敏是喘持久性的重要风险因素.
- 针对每个因素报告了特定的调整赔率比率 (aOR) 和置信区间 (CI).
结论:
- 确定了几种持续性儿童喘的独立风险因素.
- 通过将KAS和HIRA数据联系起来,可以在特定人群中澄清这些风险因素.
更多相关视频
相关概念视频
01:29Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
01:20Asthma: Pathogenesis and Management
405
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
405
01:26Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
01:24Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
01:30Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K