癌症相关的状静脉血栓症:临床影响和管理考虑
Omri Cohen1, Lucia Maria Caiano2, Sarina Levy-Mendelovich3
1National Hemophilia Center, Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel-Hashomer, Israel; School of Medicine, Tel Aviv University, Israel; Department of Medicine and Surgery, University of Insubria, Varese, Italy.
腹腔静脉血栓症 (SVT) 是腹腔静脉中罕见的血栓,与癌症有着密切的联系. 对于未引起的SVT患者来说,对恶性瘤的及时评估至关重要.
科学领域:
- 医学科学 医学科学 医学科学
- 在瘤学瘤学.
- 血液学 血液学 血液学
背景情况:
- 静脉血栓症 (SVT) 是一种不常见的静脉血栓塞栓症 (VTE),涉及腹静脉.
- SVT与腹内恶性瘤和骨髓增殖性瘤 (MPN) 有显著的关联.
研究的目的:
- 审查与癌症相关的SVT的流行病学,发病因子,风险因素和诊断.
- 强调对癌症患者进行彻底的患者评估和基于证据的SVT治疗的重要性.
主要方法:
- 关于静脉血栓症及其与癌症的关联的文献综述.
- 对临床表现,诊断方法和治疗策略的分析.
主要成果:
- 癌症患者的SVT症状可能是微妙的或无症状的,经常被误认为是原发性癌症的进展.
- 由于相关风险,无法解释的SVT需要对潜在恶性瘤或MPN进行调查.
- 与癌症相关的SVT增加了VTE延伸,复发和出血的风险,往往需要延长抗凝治疗.
结论:
- 早期发现和评估SVT对于识别潜在癌症至关重要.
- 与癌症相关的SVT的管理需要仔细考虑VTE和出血风险.
- 需要进一步研究直接口服抗凝剂 (DOAC) 对SVT治疗的安全性和有效性.
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