相关实验视频

Updated: Jul 6, 2025

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees

Published on: July 15, 2009

植入物存在引发的骨髓缩:一个范围审查

Chee Weng Yong¹, Timothy Jie Han Sng¹, Sophia Hui Jia Choo¹

¹Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, 119085, Singapore; National University Centre for Oral Health Singapore, 9 Lower Kent Ridge Road, 119085, Singapore.

Journal of stomatology, oral and maxillofacial surgery

|January 6, 2024

概括

植入物存在引发的下巴骨硬化 (IPTO) 是与药物相关的下巴骨硬化 (MRONJ) 截然不同的疾病. 证据表明机械原因随后感染,往往需要手术来解决.

科学领域:

口腔和牙面部外科手术
牙科植入物学牙科植入物学
瘤科支持性护理

背景情况:

与药物相关的下巴骨硬化 (MRONJ) 已经得到充分证实.
植入物存在引发的下骨硬化 (IPTO) 不太了解,可能与骨整合牙科植入物有关.
牙科植入物独特的机械病因被假设为IPTO.

研究的目的:

巩固关于植入物存在触发下骨硬化 (IPTO) 的证据.
为了评估患者的特征,IPTO的发病,表现和治疗.
为了区分IPTO与与药物相关的下巴骨硬化 (MRONJ).

主要方法:

根据PRISMA扩展指南进行了范围审查.
在PubMed,EMBASE,CINAHL和Cochrane图书馆的数据库中进行了搜索.
包括23篇文章描述IPTO在患者的骨整合植入物放置在抗吸收/抗血管生成疗法之前.

主要成果:

建议在植入物放置和开始抗吸收疗法之间的6个月间隔作为IPTO标准.
机械和感染过程都与IPTO的病原体产生有关.
大多数IPTO患者需要手术来解决问题.

结论:

IPTO可能代表从机械原因到二次感染的连续性.
在服用特定药物的患者中,持续的周植入炎应该引起IPTO的怀疑.
早期识别IPTO对于及时管理和转诊至关重要.

关键词:

双酸盐相关的骨骨髓折.牙植入物是如何使用的骨髓缩症骨髓缩症骨髓缩症周植入体炎周植入体炎

更多相关视频

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice

Published on: October 16, 2014

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis

Published on: July 5, 2024

相关概念视频

Osteoclasts in Bone Remodeling

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...