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Updated: Jul 6, 2025

A Macrophage-Tumor Spheroid Co-Invasion Assay
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A Macrophage-Tumor Spheroid Co-Invasion Assay

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通过双重向的牛奶外体系统重新编程与瘤相关的巨细胞,作为癌症治疗的有效单一疗法

Ying Chen1, Liang Gong2, Yulin Cao1

  • 1Wuxi Cancer Institute, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu 214062, China.; Laboratory of Cancer Epigenetics, Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, China.

Journal of controlled release : official journal of the Controlled Release Society
|January 6, 2024
PubMed
概括

针对瘤相关巨细胞 (TAMs) 中的PDL1的工程乳外体将免疫抑制M2 TAMs重编程为抗瘤的M1巨细胞. 这种新型纳米药物显示出显著的单剂抗瘤疗效,为癌症免疫治疗提供了有前途的方法.

关键词:
癌症免疫疗法癌症免疫疗法牛奶外生体是牛奶的外生体.一个纳米人体.在 PDL1 中,PDL1 是 PDL1.瘤微环境是一个微环境.与瘤相关的巨细胞.

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