晚交抗生素:一个新的代理对抗菌药物管理?
Emmanuel Piednoir1, Pascal Thibon2, Elise Fiaux3
1INSERM UMR_S1311, Universite de Caen Normandie, Caen, France.
概括
处方后延迟服用抗生素是很常见的,特别是在老年患者,慢性病患者或周末处方时. 这突出了改善抗微生物药物管理计划的潜在领域.
科学领域:
- 制药科学 制药科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 抗生素耐药性是全球主要的健康威胁,需要对抗生素使用进行仔细监测.
- 了解抗生素分发的延迟对于优化治疗坚持和抗菌药物管理至关重要.
研究的目的:
- 分析抗生素处方和药房取药之间的时间间隔.
- 为了确定与抗生素递送延迟相关的因素.
主要方法:
- 利用法国国家医疗保险报销数据库,用于2021年提供抗生素.
- 延迟分娩被定义为服用抗生素超过处方后24小时.
- 分析了207,250个抗生素处方.
主要成果:
- 9.0%的抗生素处方在发行后24小时内被取回.
- 与延迟接收相关的因素包括年龄较大,男性性别,低收入,慢性病,周末处方,夏季,封锁期和更长的距离到医疗保健提供者.
- 具体来说,65岁以上的患者出现延迟起床的几率增加了3.27倍.
结论:
- 抗生素递送延迟是一个重大问题,特别影响弱势患者群体和某些处方环境.
- 这种延迟可能表明抗生素的潜在过度使用或滥用,作为抗生素管理倡议的有价值指标.
- 进一步的研究可以验证这一指标用于改善抗生素处方和发行实践的有针对性的干预措施.
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