REVAMP试验:仍然存在关键问题 - 作者的答案
Sant-Rayn Pasricha1, Ernest Moya2, Ricardo Ataide3
1Population Health and Immunity Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Diagnostic Haematology, The Royal Melbourne Hospital, Parkville, VIC, Australia; Clinical Haematology, The Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Parkville, VIC, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC, Australia.
Lancet (London, England)
|January 6, 2024
概括
No abstract available in PubMed .
相关概念视频
Feedback Inhibition
53.9K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
53.9K
Proofreading
54.1K
Overview
54.1K
Mismatch Repair
40.1K
Overview
40.1K
Internal Receptors
70.1K
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
70.1K
Cross-reactivity
31.1K
Overview
31.1K
Feedback Loops
57.5K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
57.5K


