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与婴儿出生大小相关的母体中央脂肪度的综合测量
Emelie Lindberger1, Fredrik Ahlsson2, Katja Junus2
1Department of Women's and Children's Health, Uppsala University, 751 85, Uppsala, Sweden. emelie.lindberger@kbh.uu.se.
Scientific reports
|January 6, 2024
概括
母亲内脏脂肪深度,而不是腰围或皮下脂肪,与婴儿体型更大有关. 这一发现可能会改善孕期大婴儿 (LGA) 的产前鉴定,并降低相关风险.
科学领域:
- 围产儿医学 围产儿医学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 医学成像超声波 超声波
背景情况:
- 准确的产前识别大于妊娠年龄 (LGA) 婴儿对于减轻不良妊娠结果至关重要.
- 产妇人体测量和腹部脂肪分布是胎儿生长的潜在指标.
研究的目的:
- 评估母亲腰围 (WC),内脏脂肪 (VF) 和皮下脂肪 (SCF) 深度和婴儿出生大小之间的关联.
- 确定这些措施的结合是否可以改善LGA和小于妊娠年龄 (SGA) 婴儿的预测.
主要方法:
- 这是一项针对瑞典1240名女性 (2015-2018) 的前性队列研究.
- 在第一个产前访问时测量母亲的WC.
- 在第二个三个月异常扫描期间,通过超声波评估腹部VF和SCF深度.
- 统计分析包括ANOVA和后勤回归,经过调整以考虑混因素.
主要成果:
- 较高的母体内脏脂肪深度 (VF ≥54mm) 与较高的出生体重标准偏差得分 (BWSDS) 和LGA的几率增加有关,不管WC.
- 孕产妇的腰围 (WC ≥88厘米) 和皮下脂肪深度 (SCF ≥21毫米) 与婴儿出生大小没有显著的独立关联.
- 与单个措施相比,WC和腹部脂肪深度的结合并没有提高婴儿出生大小的预测.
结论:
- 通过超声波测量母亲内脏脂肪深度,显示了潜在的潜力,作为识别胎儿有风险的标志物.
- 目前的母亲腰围和腹部脂肪深度测量的组合在预测婴儿出生大小方面缺乏证明的价值.
- 进一步的研究可能会改进基于超声波的标记物,以改善胎儿发育异常的产前检测.
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