氨酸/氨酸激酶36诱导的表皮细胞-介质细胞过渡促进前列腺癌中多塞塔塞尔耐药性

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Tao He1, Nan-Xing Li1, Zhao-Jun Pan2

  • 1Department of Emergency Surgery, Guangdong Provincial Key Laboratory of Major Obstetric Diseases; Guangdong Provincial Clinical Research Center for Obstetrics and Gynecology; The Third Affiliated Hospital of Guangzhou Medical University, 63 DuoBao Road, Guangzhou, Guangdong, 510150, People's Republic of China.

Scientific reports
|January 6, 2024
PubMed
概括

氨酸/氨酸激酶36 (STK36) 在前列腺癌 (PCa) 中被上调,促进细胞生长和多塞素耐药性. STK36的激活可能会驱动上皮质-介质细胞过渡 (EMT),为PCa.提供潜在的治疗点.

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