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Updated: Jul 6, 2025

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
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对NRF2/β-TrCP轴的特定向促进了NASH的有益影响

Raquel Fernández-Ginés1, José Antonio Encinar2, Maribel Escoll1

  • 1Instituto de Investigaciones Biomédicas "Alberto Sols" CSIC-UAM, Instituto de Investigación Sanitaria La Paz (IdiPaz) and Department of Biochemistry, Faculty of Medicine, Autonomous University of Madrid, Madrid, Spain; Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, Madrid, Spain.

Redox biology
|January 7, 2024
PubMed
概括

一种新型的蛋白质-蛋白质相互作用抑制剂PHAR在治疗非酒精性脂肪肝炎 (NASH) 中表现有前途. 它轻微激活NRF2,在小鼠模型中保护肝脏脂肪积累和纤维化进展.

关键词:
纤维化 纤维化 纤维化纳什·纳什 (Nash Nash) 是一个名为纳什的城市.这就是NRF2的NRF2.这就是β-TrCP.

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