基于胰岛素的配方作为癌症的新兴治疗策略:全面审查
Eswara Naga Hanuma Kumar Ghali1, Pranav1, Subhash C Chauhan1
1Department of Immunology and Microbiology, School of Medicine, The University of Texas Rio Grande Valley, McAllen, TX 78504, USA; South Texas Center of Excellence in Cancer Research, School of Medicine, University of Texas Rio Grande Valley, McAllen, TX 78504, USA.
天然益生菌纤维的胰岛素在癌症治疗中表现有前途,因为它充当药物输送载体,并表现出协同作用,免疫调节和抗癌作用. 本综述探讨了用于先进的癌症治疗和药物输送系统的以胰岛素为基础的纳米材料.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
- 在瘤学瘤学.
背景情况:
- 癌症是导致死亡的首要原因,化疗往往会引起严重的副作用,原因是药物暴露在非目标药物中.
- 益生菌纤维的胰岛素因其潜在的健康益处和癌症治疗中的治疗应用而引起了人们的注意.
- 传统的癌症疗法在药物输送和管理不良影响方面面临挑战,突出了需要创新的方法.
研究的目的:
- 审查用于医疗保健应用的以胰岛素为基础的纳米材料和纳米复合材料的发展.
- 强调胰岛素在癌症治疗中的多功能作用,包括其协同作用,信号,免疫调节和抗癌性质.
- 提供有关基于胰岛素的癌症治疗的当前临床试验和观察性研究的概述.
主要方法:
- 关于用于癌症治疗的基于胰岛素的纳米材料的最新研究的文献综述.
- 在药物输送应用中分析胰岛素的特性 (结构,稳定性,营养价值).
- 基于胰岛素的纳米复合材料的合成和表征,用于向癌症治疗.
主要成果:
- 基于胰岛素的纳米材料显示出作为癌症治疗中向药物输送的有效载体的潜力.
- 胰岛素作为一种多功能剂,通过协同作用,免疫调节和抗癌机制增强治疗效果.
- 新兴的临床研究表明,基于胰岛素的干预措施在癌症管理中的结果很有希望.
结论:
- 基于胰岛素的纳米材料为克服传统化疗的局限性和改善癌症治疗结果提供了一个有希望的策略.
- 胰岛素的独特特性使其成为开发新型治疗剂和瘤学药物输送系统的宝贵组成部分.
- 需要进一步的研究和临床评估,以充分探索胰岛素在抗癌方面的治疗潜力.
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