对具有抗菌作用的核酸 (PNA) 进行系统审查:有效性,潜力和挑战

Mohamed El-Fateh1, Anushree Chatterjee2, Xin Zhao3

  • 1Department of Animal Science, McGill University, Sainte-Anne-de-Bellevue, QC, Canada, H9X3V9; Department of Hygiene and Zoonoses, Faculty of Veterinary Medicine, Mansoura University, 35516, El-Dakhelia, Egypt; Antimicrobial Regeneration Consortium Labs, Louisville, CO, 80027, USA.

概括

核酸 (PNA) 通过向细菌mRNA,显示出作为抗菌剂的前景. 本综述分析了PNA的有效性和设计,以开发针对抗生素耐药细菌的新疗法.