老年人短期素食挑战对代谢和炎症参数的影响 - 一项随机对照交叉研究
Lary Döschner1, Kora Schulze1, Lea Göger2
1Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117, Berlin, Germany.
Molecular nutrition & food research
|January 7, 2024
概括
短期素食饮食改善了胰岛素敏感性,并减少了老年人的炎症. 然而,满足蛋白质需求是具有挑战性的,这表明需要仔细规划老年人素食饮食.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 代谢健康 代谢健康
背景情况:
- 长期的素食饮食可能会导致老年人营养缺乏的风险.
- 短期纯素饮食在年轻人中显示出积极的代谢效应.
- 调查短期素食饮食的可行性和对老年人的影响至关重要.
研究的目的:
- 评估老年人48小时素食饮食的可行性.
- 评估短期素食饮食对代谢和炎症标志物的影响.
- 了解对胰岛素平衡和营养摄入的影响.
主要方法:
- 随机对照交叉研究与30名健康的老年人 (≥65岁).
- 参与者遵循了48小时的ad libitum素食饮食和48小时的杂食饮食.
- 分析饮食摄入量,代谢标志物 (葡萄糖,胰岛素,甘油三,hsCRP) 和体重.
主要成果:
- 素食饮食导致蛋白质,脂肪和热量摄入量降低,碳水化合物和纤维摄入量更高.
- 在素食饮食后观察到胰岛素度和胰岛素抵抗的显著降低.
- 血清葡萄糖,甘油三,hsCRP和体重的降低,在患有轻度炎症的参与者中显著改善.
结论:
- 短期素食饮食可以改善老年人胰岛素平衡.
- 在短期素食饮食中满足蛋白质需求是具有挑战性的,尽管有咨询.
- 需要进一步的研究,以确保在老年人短期素食干预期间提供足够的营养.
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