神经响应属性预测被感知的内容和位置,由人类听觉皮层的内电刺激引起
Qian Wang1,2,3, Lu Luo4, Na Xu5
1School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing 100871, China.
Cerebral cortex (New York, N.Y. : 1991)
|January 8, 2024
概括
听觉皮层的内电刺激 (iES) 可以唤起声音. 神经特征,包括内脑电图 (iEEG) 信号中的高马和α特征,可以预测感知到的声音内容和位置.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 人类电生理学 人类电生理学
背景情况:
- 听觉皮层的内电刺激 (iES) 可以诱发诸如幻觉或幻觉之类的听觉感觉.
- 驱动感知声音内容和位置变化的神经机制仍然不清楚.
研究的目的:
- 调查iES在人类听觉皮层中引起的异质声音体验背后的神经机制.
- 识别不同的神经特征来感知声音内容和位置.
主要方法:
- 收集了28名患者在3062个内部位接受iES的主观报告.
- 确定了113个听觉皮质部位,引起声音体验.
- 使用时间频率分解分析了内脑电图 (iEEG) 信号.
主要成果:
- 通过iEEG的早期高马 (γ) 特征预测感知到的声音内容.
- 感知到的声音位置与幻觉的晚期高γ特征和幻觉的长期α (α) 特征有关.
结论:
- 独特的神经特征 (早期高γ,晚期高γ和α特征) 区分iES引起的声音体验.
- 这项研究提供了对听觉感知神经基础的见解,并提供了恢复听觉的潜在策略.
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