[在体检人群中研究甲状腺结节和代谢指数之间的相关性]
1Laboratory Medicine Center, Affiliated Hospital of Nantong University, Nantong 226001, China.
概括
甲状腺结节 (TN) 在南通普遍存在,影响了超过一半的受试者. 较低的禁食血糖 (FBG) 水平被确定为预防TN发展的保护因素.
科学领域:
- 内分泌学和新陈代谢学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 甲状腺结节 (TN) 是一个严重的健康问题,其患病率因地区和人口因素而异.
- 了解TN的流行病学特征和风险因素对于制定有效的预防和早期干预策略至关重要.
研究的目的:
- 确定在南通地区接受体检的人群中甲状腺结节 (TN) 的患病率和影响因素.
- 为TN的早期预防和干预提供理论基础.
主要方法:
- 一项涉及6950名参与者的横截面研究,他们接受了体检和高分辨率超声波.
- 收集人口统计数据,人类测量 (身高,BMI,血压) 和代谢指标 (FBG,TC,TG,LDL-C,HDL-C,UA,HCY).
- 使用SPSS进行统计分析,包括t测试,曼-惠特尼U测试,克鲁斯卡尔-瓦利斯测试和后勤回归模型.
主要成果:
- 总体TN的患病率为53.97%,女性 (68.47%) 比男性 (47.08%) 显著高.
- 随着年龄的增长,TN的患病率在两种性别中都增加.
- 在性别之间观察到风险因素的显著差异,空腹血糖 (FBG) <6.1 mmol/L在多变量分析中被确定为保护因素.
结论:
- 甲状腺结节的患病率在南通地区很高,女性性别和年龄的增加是关键的危险因素.
- 代谢指标,特别是禁食血糖,在TN发育中发挥着重要作用.
- 对于具有异常代谢指标的个体,建议加强健康查和管理.
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