在加拿大进行计算机断层扫描检查的患者的器官剂量重建 1992-2019年
Choonsik Lee1, Brian Moroz2, Christopher Thome3,4
1Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, 20850, United States.
Radiation protection dosimetry
|January 8, 2024
概括
这项研究为加拿大CT扫描 (1992-2019) 创建了一个全面的器官剂量库. 它揭示了2000年后辐射剂量的显著降低,有助于辐射风险分析.
科学领域:
- 医学物理 医学物理
- 放射学 放射学是一门学科.
- 辐射流行病学 辐射流行病学
背景情况:
- 计算机断层扫描 (CT) 是重要的诊断工具,但涉及辐射暴露.
- 准确的剂量测量对于评估与医学成像相关的长期健康风险至关重要.
- 对于加拿大的不同患者人群而言,缺乏一个全面的器官剂量库.
研究的目的:
- 为从1992年到2019年接受CT扫描的加拿大儿科和成人患者开发第一个器官剂量库.
- 通过提供详细的器官剂量数据来支持有关辐射风险的流行病学研究.
- 分析器官吸收剂量的趋势随着时间的推移和患者特征.
主要方法:
- 模拟计算机断层扫描剂量指数 (CTDI) 值使用国家调查数据 (加拿大/英国) 基于患者年龄,扫描区域和年 (1992-2019).
- 使用国家癌症研究所CT剂量计系统和剂量转换系数库将CTDI值转换为器官吸收剂量.
- 编制了33个器官和组织的剂量库,按患者年龄,性别,扫描区域和年份分层.
主要成果:
- 在2000年之前接受最高剂量的确定的器官:活跃的骨髓 (头部扫描),肺部 (胸部扫描) 和结肠 (腹腔盆腔扫描).
- 2000年后观察到显著的剂量减少:24%的儿科头部/干和成人头部扫描,55%的成人干扫描.
- 建立了一个详细的器官剂量库,适用于加拿大CT患者队列.
结论:
- 开发的器官剂量库为加拿大CT患者的辐射风险评估提供了关键数据.
- 2000年以后CT辐射剂量的显著减少表明扫描协议或技术的改进.
- 这一资源将促进未来对辐射引起的健康影响的流行病学分析.
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