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正常体重中部肥胖是突然感官神经听力损失的预后不良因素

Shih-Wei Wang¹, Shu-Yu Tai^2,3, Chin-Kuo Chen⁴

¹Department of Otorhinolaryngology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

The Annals of otology, rhinology, and laryngology

|January 8, 2024

概括

正常体重中心肥胖 (NWCO) 可能会对突然感觉神经听力损失 (SSNHL) 的恢复产生负面影响. 这一发现表明NWCO是SSNHL预后的一个重要因素,独立于整体体重指数.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
代谢健康代谢健康
听力学听力学是指听力学.

背景情况:

突发感神经听力损失 (SSNHL) 是一种具有可变预后的耳科紧急情况.
中部肥胖,特别是在正常体重的个体 (NWCO) 中,越来越多地被认为是代谢风险因素.
NWCO对SSNHL结果的具体影响仍未得到充分研究.

研究的目的:

调查正常体重中心肥胖症 (NWCO) 与突然神经感官听力损失 (SSNHL) 的预后之间的关联.
分析身体质量指数 (BMI) 和中心肥胖症在SSNHL恢复中的作用.
确定影响SSNHL结果的潜在风险因素.

主要方法:

在高雄医科大学医院对2008-2019年807例SSNHL病例进行了回顾性分析.
将患者分为非肥胖 (BMI <24 kg/m2) 和超重/肥胖 (BMI ≥24 kg/m2) 的两组.
进一步分层为正常体重非中心肥胖 (NWNCO) 和正常体重中心肥胖 (NWCO) 组.
包括多变量逻辑回归在内的统计分析,以评估肥胖参数与SSNHL预后之间的关联.

主要成果:

总体BMI与非肥胖群和超重/肥胖群之间的SSNHL恢复率没有显著的相关性 (P=.9048).
与NWNCO (48.50%) (P=.0371) 患者相比,NWCO患者的良好预后率 (35.06%) 显着较低.
多变量分析确定NWCO是与较差的SSNHL恢复相关的重要独立因素 (aOR=2.51,P=.0075).

结论:

正常体重中心肥胖 (NWCO) 是突然感官神经听力损失 (SSNHL) 不利预后的重要独立预测因素.
临床医生应该考虑评估正常体重患者的SSNHL的中心脂肪.
针对中心肥胖症可能提供一种潜在的治疗策略,以改善SSNHL结果.

关键词:

中央肥胖中心肥胖中心正常体重中心肥胖 (NWCO)肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖预后预后预后突发的感觉神经听力损失 (SSNHL)

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