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绿色合成的铜氧化物纳米颗粒通过Terminalia chebula合成的干果提取物:特征和抗菌作用

Tharani Munusamy¹, Rajeshkumar Shanmugam¹

¹Department of Pharmacology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.

|January 8, 2024

概括

使用Terminalia chebula提取物合成了环保的氧化铜纳米颗粒 (CuONPs). 这些TCF-CuONP对伤口病原体如Pseudomonas aeruginosa具有显著的抗菌活性.

科学领域:

纳米技术纳米技术
材料科学材料科学材料科学
绿色化学绿色化学

背景情况:

氧化铜纳米颗粒 (CuONPs) 正在研究其抗菌特性.
伤口病原体在医疗保健环境中构成了重大挑战.
开发可持续和有效的抗菌剂至关重要.

研究的目的:

使用Terminalia chebula干果提取物合成氧化铜纳米粒子 (CuONPs).
为了描述合成的TCF-CuONPs.
评估TCF-CuONP对伤口病原体的抗菌疗效.

主要方法:

使用Terminalia chebula提取物进行CuONPs的绿色合成.
通过UV-Vis光谱,SEM,EDX和TEM进行表征.
抗菌分析包括阿加井扩散,时间杀死曲线,蛋白质泄漏和抗菌膜对S. aureus,P. aeruginosa和E. coli的分析.

主要成果:

紫外线-Vis光谱显示在440nm处的峰值.
SEM证实了球形形态;EDX证实了铜的存在.
TEM显示了10-12nm的CuONP.
TCF-CuONPs表现出显著的抗菌活性,特别是针对Pseudomonas aeruginosa.

结论:

通过使用T. chebula提取物成功合成和表征环保CuONPs.
TCF-CuONPs对关键的伤口病原体具有强大的抗菌活性.
这些发现支持TCF-CuONPs在伤口管理和可持续医疗保健解决方案方面的潜力.

关键词:

抗菌剂是一种抗菌剂.铜氧化物纳米粒子铜氧化物纳米粒子环保友好的环保友好的终端骨骨的终端伤口病原体的病原体

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