临床药剂师在抗菌药物管理计划 (ASP) 中的作用:系统审查
Ibrahim M Dighriri1, Bayader A Alnomci2, Mashael M Aljahdali3
1Department of Pharmacy, King Abdulaziz Specialist Hospital, Taif, SAU.
Cureus
|January 8, 2024
概括
药剂师在抗菌药物管理计划 (ASP) 中至关重要,改善抗生素处方和减少使用. 他们的干预措施优化治疗和降低成本,在医院中显示出显著的价值.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 抗菌素耐药性 (AMR) 构成一个重大的全球健康挑战,死亡率和医疗保健支出不断上升.
- 抗生素管理计划 (ASP) 对于优化抗生素利用和减轻耐药性至关重要.
- 医院ASP中药剂师的作用需要全面评估.
研究的目的:
- 系统地审查和综合有关药剂师在医院ASP中的作用和影响的证据.
- 评估药剂师主导的药物管理干预措施对抗生素处方和患者结果的有效性.
主要方法:
- 在主要数据库中对2016年至2023年间发表的研究进行了系统的文献搜索.
- 纳入标准用于确定24项相关研究,包括观察性和随机临床试验.
- 数据提取集中在药剂师活动,干预影响和患者结果上.
主要成果:
- 药剂师从事各种管理活动,包括前性审计,配方管理和指导方针制定.
- 药剂师主导的干预措施显著改善了抗生素的处方,减少了不必要的使用,并优化了治疗.
- 关键结果包括降低最佳抗生素的时间,加强指导方针的遵守,减少抗生素持续时间和节省成本.
结论:
- 药剂师在医院ASP中发挥着关键作用,明显改善了抗生素的使用和患者的治疗结果.
- 有证据支持将药剂师纳入和扩展到管理活动中,包括门诊设置.
- 虽然对抗药性和死亡率的直接影响需要进一步调查,但目前的发现强调了药剂师参与的价值.
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