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我们是否应该扩大糖尿病患者脏活检的适用范围? 利的部分是有利的部分

Loreto Gesualdo¹, Marco Fiorentino¹, Francesca Conserva¹

¹Renal, Dialysis and Transplantation Unit, Department of Precision and Regenerative Medicine and Ionian Area (DIMEPRE-J), University of Bari, Bari, Italy.

Clinical kidney journal

|January 8, 2024

概括

组织病理学有助于在糖尿病患者中诊断糖尿病病 (DN) 和非糖尿病病 (NDRD). 将组织病理学与其他数据相结合,可以改进个性化治疗策略,以获得更好的患者结果.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
内分泌学在内分泌学.
病理学病理学病理学

背景情况:

糖尿病病 (DN) 和非糖尿病病 (NDRD) 在管理全球糖尿病流行病方面带来了重大挑战.
准确的诊断和量身定制的治疗对于减轻糖尿病患者脏并发症至关重要.
组织病理学分析是理解损伤多样化的关键.

研究的目的:

突出组织病理学在区分DN和NDRD在糖尿病患者中的重要性.
探索组织病理学发现如何改进诊断策略和个性化治疗干预.
强调将组织病理学与其他数据类型的整合,以改善患者护理.

主要方法:

对糖尿病患者脏活检中的组织病理学发现的综述.
对糖尿病病的分类系统的分析,如国际病理学会的共识.
检查球和管间病变之间的相关性.

主要成果:

组织病理学区分了经典的糖尿病血球样硬化 (DN),血管/缺血性变化 (NDRD) 和混合形式.
国际病学学会的分类对DN进行了分层,有助于预后.
损害现象型中的组织病理异质性是显而易见的,影响治疗方法.

结论:

组织病理学检查对于准确的诊断和了解糖尿病中损伤异质性是不可或缺的.
将基因病理学与临床,奥米克和成像数据相结合,可以实现个性化的治疗策略.
协作努力和像iBeat研究这样的先进举措对于推进糖尿病病管理至关重要.

关键词:

慢性脏疾病慢性脏疾病这是分类分类的分类.糖尿病糖尿病患者糖尿病患者现象类型现象类型精准医学是一门精准医学.

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