住院患者Q热的频率正在上升
Mohamad Alhoda Mohamad Alahmad1, Kassem A Hammoud2
1University of Kansas Medical Center, Department of General Internal Medicine, Kansas City, KS, USA.
概括
美国因Q热,一种Coxilla burnetii感染而住院的病例正在增加. 这种细菌感染与传染性内心炎和更高的住院患者死亡率有显著联系.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 热是一种由Coxiella burnetii引起的动物性细菌感染.
- 在美国,这是一种必须报告的疾病,通常表现为无症状或自我限制的发烧性疾病,肝炎或肺炎.
- 慢性Q热,通常是传染性内心炎,会影响免疫力低下的人或患有膜病变的人.
研究的目的:
- 调查美国Q热的住院病例频率和趋势.
- 确定与Q热病住院相关的常见并发症和结果.
主要方法:
- 从2010年到2019年使用全国住院患者样本 (NIS) 的回顾性队列研究.
- 采用了调查程序和统计分析,包括千平方,最小平方平均值和Jonckheere-Terpstra测试.
- 数据挖掘和分析使用SAS 9.4.4进行.
主要成果:
- 总共有2685例Q热住院病例被确定.
- 传染性内心炎是最常见的心脏并发症 (17%的病例),并与住院患者死亡率增加有关 (p<0.001).
- 观察到Q热病例的增加趋势,包括内心炎或没有内心炎 (p<0.05),太平洋和南大西洋地区的患病率更高.
结论:
- 医生应该认识到住院Q热患者的上升趋势.
- 在Q热和传染性内心炎之间显著的联系需要临床关注.
- 进一步的研究是必要的,以了解和有效管理Q热.
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