瘤微环境中的转移研究器官芯片应用的新兴趋势:全面的文献计量分析
Chunrong He1, Fangfang Lu2, Yi Liu1
1Department of Orthopaedics, The Second Affiliated Hospital, University of South China, Hengyang, Hunan, China.
Heliyon
|January 8, 2024
概括
器官芯片技术正在彻底改变疾病建模和药物开发,特别是在瘤微环境研究中. 本文献分析突出了全球趋势和该领域的关键参与者,指导了未来的研究方向.
科学领域:
- 生物医学工程 生物医学工程
- 翻译医学是一种翻译医学.
- 药物发现 药物发现 药物发现
背景情况:
- 器官芯片技术对于推进疾病建模,药物开发和精准医学至关重要.
- 这项技术在研究瘤微环境中的转移方面显著有前途.
- 全球对芯片器官研究的科学贡献正在迅速扩大.
研究的目的:
- 对全球关于器官芯片技术的科学成果进行全面的文献计量分析.
- 确定关键的研究趋势,主导国家,机构和有影响力的研究人员.
- 绘制新兴研究前沿和现场合作机会的地图.
主要方法:
- 对2014年至2023年间发表的2305篇文章进行了图书统计分析.
- 数据来源于科学网络核心集合数据库.
- 使用VOSviewer,CiteSpace和R-bibliometrix软件进行的分析.
主要成果:
- 2014-2023年全球出版物的持续上升趋势表明持续增长.
- 美国和中国是有着强大的国际合作关系的领先贡献者.
- 关键机构包括哈佛大学,麻省理工学院和中国科学院;著名的研究人员包括唐纳德·英格伯和尤·斯里克·张.
- 领先的期刊是芯片实验室,微机器和生物工程和生物技术的前沿.
- 新兴的研究领域包括瘤微环境和转移,药物发现应用和个性化医学.
结论:
- 器官芯片技术显著影响了解疾病机制和药物相互作用,特别是在瘤学中.
- 这种文献计量分析为研究人员和临床医生提供了宝贵的见解,突出了合作和未来调查的关键领域.
- 该领域准备继续增长和创新,推动医学进步.
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