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脉冲振荡计及其在慢性阻塞性肺病诊断中的独立作用
Kuang-Yu Chen1, Ming-Hui Hung1, Kuo-Chin Kao2,3
1Chest Medicine, Lo-Tung Poh-Ai Hospital, No. 83, Nanchang Street, Luodong Township, Yilan County 265, Taiwan.
Heliyon
|January 8, 2024
概括
脉冲振荡计 (IOS) 可以预测慢性阻塞性肺病 (COPD) 的诊断. 通过IOS测量的体重指数调整的气道阻力显示了诊断COPD的潜力,肥胖和非肥胖个体的切断值不同.
科学领域:
- 肺部医学 肺部医学
- 呼吸系统诊断 呼吸系统诊断
背景情况:
- 肺功能检测 (PFT) 在COVID-19患者中具有挑战性,因为强制到期要求.
- 脉冲振荡计 (IOS) 通过最大限度地减少气溶生成,提供了更安全的替代方案.
- 本研究探讨了用于诊断COPD的IOS和螺旋计之间的关系.
研究的目的:
- 为了研究脉冲振荡计 (IOS) 和螺旋计之间的相关性.
- 确定IOS是否可以准确预测慢性阻塞性肺病 (COPD) 的基于螺旋计的诊断.
主要方法:
- 对115名患者进行了回顾性分析,这些患者接受了螺旋计和IOS.
- 将患者分为COPD和非COPD组的分层基于螺旋计.
- 接收机操作员特征 (ROC) 曲线分析,以评估IOS用于高级COPD预测 (BD后FEV1 / FVC<0.6).
主要成果:
- 对COPD诊断进行了评估,以体重指数 (BMI) 调整的气道阻力和反应下面积 (AX) 进行了评估.
- 经BMI调整的气道阻力显示,在预测晚期COPD时,曲线下面的面积比AX (0.782) 更大.
- 经BMI调整的气道阻力值>160适度预测基于螺旋计的COPD诊断.
结论:
- 根据BMI调整的呼吸道阻力是基于螺旋计的COPD诊断的一个有希望的预测指标.
- 根据BMI调整的气道阻力最佳截止值在肥胖和非肥胖个体之间有所不同.
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