一个多维模型的老年人的记忆抱怨和相关的枢纽区域
Véronique Paban1, A Mheich2, L Spieser1
1Aix-Marseille Université, CNRS, LNC (Laboratoire de Neurosciences Cognitives-UMR 7291), Marseille, France.
Frontiers in aging neuroscience
|January 8, 2024
概括
主观认知衰退 (SCD) 与大脑网络的变化有关. 较低的自尊和良心与记忆障碍相关,这表明SCD中潜在的补偿性大脑重新连接.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 老年学是一门学科.
背景情况:
- 记忆障碍在老年人和主观认知衰退 (SCD) 患者中很常见.
- SCD对于早期发现痴呆症至关重要.
- 了解SCD的认知和心理因素是必不可少的.
研究的目的:
- 识别导致SCD记忆障碍的认知/心理因素.
- 在患有SCD的个体中描述大脑网络枢纽的变化.
- 探索SCD中补偿机制的神经基础.
主要方法:
- 结构方程建模用于分析心理因素 (自尊,良心等) 之间的关系. 和记忆的投诉.
- 分析了休息期间的脑电图 (EEG) 德尔塔和塔波段.
- 中间中心性被用来识别大脑网络枢纽.
主要成果:
- 自尊和良心显著影响了记忆力投诉.
- 特定的大脑区域改变了他们在SCD中的枢纽状态.
- 下卷和左侧轨道前皮层成为枢纽,而背侧前额皮层和中卷失去枢纽地位.
结论:
- 自尊和良心等心理因素在与SCD相关的记忆抱怨中发挥作用.
- SCD涉及大脑网络拓学的重大变化,其中区域转移了枢纽角色.
- 这种神经重新连接可能代表一个补偿性大脑机制,以维持面对SCD的功能.
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