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在过去的30年里,对膝关节骨关节炎的炎症机制进行了图书统计分析

Yiyi Chen¹, Bo Yu¹, Fei He¹

¹Orthopaedic Rehabilitation Unit, Department of Rehabilitation Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China.

American journal of clinical and experimental immunology

|January 8, 2024

概括

这项研究对膝关节骨关节炎 (KOA) 炎症的研究进行了绘制,确定了关键趋势和知识差距. 这些发现指导了未来的治疗方法,以改善KOA患者的疼痛管理.

科学领域:

生物医学科学生物医学科学
类风湿病学类风湿病学
免疫学免疫学免疫学

背景情况:

膝关节骨关节炎 (KOA) 构成了重大的治疗挑战,需要对其炎症基础有更深入的了解.
目前KOA炎症的研究趋势需要进行系统分析,以确定知识框架和未来方向.

研究的目的:

分析有关膝关节骨关节炎 (KOA) 炎症机制的全球研究环境.
确定KOA炎症的关键研究热点,合作和新兴趋势.
为开发改善KOA疼痛控制治疗策略提供见解.

主要方法:

从Web of Science核心收藏中对1083篇发表到2023年7月31日的文章进行了图书统计分析.
利用视觉化工具,包括CiteSpace,VOS Viewer和Tableau来分析研究趋势,关键字的共同出现和机构合作.
专注于关节软骨,突膜,子突骨和KOA中的突液中的信号通路.

主要成果:

中国和美国在KOA炎症研究生产率方面是领先的国家.
像加州大学系统和杜克大学这样的关键机构是突出的.
高度相关的关键词包括"表达"",类风湿性关节炎"",关节软骨"",NF-kappa B"和"结膜液".

结论:

图书统计分析揭示了KOA炎症机制的当前知识框架和研究前沿.
了解这些机制,包括信号通路和治疗试剂,对于推进KOA疗法至关重要.
未来的研究应该探索途径相互作用和注射治疗对KOA炎症的疗法的疗效.

关键词:

膝关节关节炎 (KOA) 是一种疾病.热点地区热点地区炎症机制的炎症机制是什么知识框架知识框架知识框架三角测量分析三角测量分析

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