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Updated: Jul 6, 2025

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大量LMM:使用线性混合模型对多个定量特征进行实时基因组扫描

Zifan Yu1, Gregory Farage1, Robert W Williams2

  • 1Department of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

bioRxiv : the preprint server for biology
|January 8, 2024
PubMed
概括

研究人员开发了BulkLMM,这是一种用于快速基因组扫描的新算法. 这种方法显著加快了使用线性混合模型 (LMM) 分析众多定量特征的速度,使遗传研究更有效率.

关键词:
计算计算是指计算机的使用.基因组扫描扫描是为了检查基因.朱莉亚 朱莉亚 朱莉亚 朱莉亚 朱莉亚线性混合模型 线性混合模型一个平行的平行.

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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