新生儿肠杆菌吸收人乳养婴儿消化液中的细胞外囊泡
bioRxiv : the preprint server for biology
|January 8, 2024
概括
人类牛奶细胞外囊泡 (HMEVs) 能够在新生儿消化过程中存活下来,并被肠道细胞吸收. 这一发现支持HMEV在婴儿营养和治疗方面的潜在用途.
科学领域:
- 生物化学 生物化学
- 细胞生物学 细胞生物学
- 新生儿营养新生儿营养
背景情况:
- 人类牛奶细胞外囊泡 (HMEVs) 显示出临床前有望提高肠道功能和减少炎症.
- 新生儿人类消化系统中HMEVs的生存和吸收仍然没有特征,限制了它们的治疗和营养应用.
结论:
- 细胞外囊泡可以从新生儿的消化液中成功分离出来.
- 新生儿肠上皮细胞积极吸收这些来自消化器的细胞外囊泡 (dEVs).
- 这些发现表明,HMEVs可能可以在新生儿消化过程中存活下来并被吸收,为婴儿营养和治疗策略开辟了道路.
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