Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

3.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
3.9K
Anatomy of the Intestines01:23

Anatomy of the Intestines

72.0K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.0K
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

71.2K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Complex adaptive architectures constrain the pace of adaptations sweeping across human gut microbiomes.

bioRxiv : the preprint server for biology·2026
Same author

The persistence and loss of hard selective sweeps amid admixture in ancient Eurasians.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Uniform bacterial genetic diversity along the gut.

Nature communications·2026
Same author

Nasal cutaneous impact of non-invasive respiratory support for extremely preterm neonates: a descriptive, prospective, multicenter study.

European journal of pediatrics·2026
Same author

Gene-specific selective sweeps are pervasive across human gut microbiomes.

Nature·2025
Same author

Uniform bacterial genetic diversity along the guts of mice inoculated with human stool.

bioRxiv : the preprint server for biology·2025

相关实验视频

Updated: Jul 6, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.0K

在人类肠道微生物组中,普遍的选择性扫描.

Richard Wolff1, Nandita R Garud1,2

  • 1Department of Ecology and Evolutionary Biology, UCLA.

bioRxiv : the preprint server for biology
|January 8, 2024
PubMed
概括

科学家们在人类肠道微生物群中发现了300多个适应实例,揭示了饮食如何塑造微生物进化. 这项研究强调了碳水化合物代谢的选择性扫描,特别是在西方化人口中使用马尔托德克斯.

科学领域:

  • 微生物进化过程中的微生物.
  • 人类微生物组研究研究
  • 人口遗传学 人口遗传学

背景情况:

  • 人的肠道微生物组包括多样化,不断进化的物种,受宿主选择压力的影响.
  • 了解常见的适应性揭示了微生物组功能和宿主特征的关键驱动因素.
  • 缺乏对广泛的微生物群适应性的系统扫描.

研究的目的:

  • 系统地识别已经在人类肠道微生物群中传播的适应性.
  • 开发一种新的统计方法来检测适应性单双型的传播.
  • 研究饮食在推动微生物组进化中的作用.

主要方法:

  • 开发了综合链接不平衡评分 (iLDS) 来检测适应性单双型传播.
  • 应用iLDS对来自24个全球人口的~30种普遍存在的开始性肠道物种.
  • 分析了选择性扫描,重点关注碳水化合物代谢和人口特异性差异.

主要成果:

  • 在各种肠道物种中确定了300多个选择性扫描.
  • 在碳水化合物代谢位置中发现了扫描的丰富,这表明了饮食适应.
  • 观察到西方化和非西方化人口之间选择目标的显著差异.
  • 发现了西化人口中独特的马尔托德素代谢扫描.

更多相关视频

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing
08:05

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

19.7K
High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health
11:40

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

Published on: April 28, 2022

2.8K

相关实验视频

Last Updated: Jul 6, 2025

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

28.0K
Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing
08:05

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing

Published on: March 19, 2018

19.7K
High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health
11:40

High-Throughput Screening of Microbial Isolates with Impact on Caenorhabditis elegans Health

Published on: April 28, 2022

2.8K

结论:

  • 选择性扫描在人类肠道微生物组进化中很常见.
  • 主体饮食显著影响微生物选择的目标.
  • 微生物适应反映了对饮食成分的反应,例如西方饮食中的马尔托德.