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Updated: Jul 6, 2025

Author Spotlight: Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment
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瘤微环境中的空间和组成生物标志物预测了三阴性乳腺癌的临床结果

Haoyang Mi1, Ravi Varadhan2, Ashley M Cimino-Mathews3

  • 1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States.

bioRxiv : the preprint server for biology
|January 8, 2024
PubMed
概括

三重阴性乳腺癌 (TNBC) 研究揭示了与生存相关的瘤微环境 (TME) 模式. 空间分析确定了预测TNBC患者治疗反应的细胞社区.

关键词:
蜂社区 蜂社区临床试验 临床试验是指临床试验.深度学习是一种深度学习.免疫瘤学 免疫瘤学新型TRIP就是新型TRIP.预测生物标志物预测生物标志物三阴性乳腺癌是三阴性乳腺癌.瘤微环境是一个微环境.空间建筑的空间建筑.

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The Tumor Microenvironment02:17

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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