在初始杂交后,基因组进化令人惊地可预测
Quinn K Langdon1,2,3, Jeffrey S Groh4, Stepfanie M Aguillon1,2,5
1Department of Biology, Stanford University.
bioRxiv : the preprint server for biology
|January 8, 2024
概括
杂交结果是可重复的,自然选择在独立的鱼群中驱动一致的遗传模式. 在几代人的祖先中这种稳定性凸显了杂交后选择的可预测影响.
科学领域:
- 进化生物学 进化生物学
- 基因组学就是基因组学.
- 规格 规格 规格 规格
背景情况:
- 杂交,或物种之间的遗传交换,在生命树上是常见的.
- 许多物种的基因组包含来自相关物种的DNA,这引发了关于可重复性和自然选择作用的问题.
- 有限的实证系统阻碍了对杂交中的基因组结果的研究.
研究的目的:
- 在独立形成的杂交种群中研究基因组结果的重复性.
- 为了确定自然选择在杂交后在多大程度上驱动本地祖先的可重复模式.
- 为了比较跨混合种群的重复性,具有不同程度的进化分歧.
主要方法:
- 利用独立形成的剑尾鱼 (Xiphophorus birchmanni和X. cortezi) 的杂交种群.
- 应用了新的分析方法来评估当地祖先模式及其在人群之间的可预测性.
- 集成时间序列数据来追踪大约40代人的祖先稳定性.
主要成果:
- 一个杂交群体中的本地祖先模式对一个单独的,独立的群体中的情况具有很高的预测性.
- 早期几代人的强烈自然选择对当地祖先的观察到的可重复性作出了重大贡献.
- 选择中的地区在40代以上表现出稳定的祖先.
- 在X. birchmanni和X. cortezi之间的杂交物表现出比X. birchmanni和X. malinche杂交物更强的选择和更高的重复性.
结论:
- 杂交的基因组结果非常可重复,即使是在人口统计学上独立的种群中.
- 自然选择在混合后塑造和稳定当地祖先模式方面发挥着至关重要的作用.
- 父母物种之间更大的进化分歧导致混合基因组中更强的选择和更高的重复性.
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