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Updated: Jul 6, 2025

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT

Published on: January 7, 2018

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衰老对老鼠葡萄糖和脂质代谢的影响

Evan C Lien1,2, Ngoc Vu3, Anna M Westermark2

  • 1Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.

bioRxiv : the preprint server for biology
|January 8, 2024
PubMed
概括

健康的衰老维持葡萄糖代谢和NAD+水平,脂质代谢可能缓冲大脑等组织中与年龄相关的变化.

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Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
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