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Updated: Jul 6, 2025

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在结肠癌中,对治疗耐药的循环瘤细胞进行表观基因学重编程

Aida Bao-Caamano1,2,3, Nicolás Costa-Fraga1,2,3, Laure Cayrefourcq4,5

  • 1Epigenomics Unit, Cancer Epigenomics, Translational Medical Oncology Group (ONCOMET), Health Research Institute of Santiago de Compostela (IDIS), University Clinical Hospital of Santiago (CHUS/SERGAS), Santiago de Compostela, Spain.

Frontiers in cell and developmental biology
|January 8, 2024
PubMed
概括

循环瘤细胞 (CTC) 的表观遗传变化,特别是DNA甲基化,是了解结直肠癌治疗耐药性的关键. 耐药的CTC表现出低甲基化特征,揭示了潜在的新生物标志物和药物标.

关键词:
通过DNA甲基化.表观基因组学是指表观基因组学.生物标志物 生物标志物结肠直肠癌是什么意思具有转移能力的CTC.治疗目标是治疗的目标.治疗耐药性 治疗耐药性

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