相关实验视频

Updated: Jul 6, 2025

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

皮层灰白质对比异常在男性儿童注意力缺陷多动症障碍

Changhao Wang^1,2, Yanyong Shen^1,2, Meiying Cheng^1,2

¹Department of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Frontiers in human neuroscience

|January 8, 2024

概括

研究人员在使用灰白质对比度 (GWC) 的男性儿童中发现了注意力缺陷多动性障碍 (ADHD) 的大脑微观结构改变. 特定地区显示高GWC,与注意力缺失严重程度相关.

科学领域:

神经科学是一个神经科学.
发育神经科学的发展神经科学.
神经成像是一种神经成像.

背景情况:

注意缺陷多动症 (ADHD) 研究通常集中在整个大脑体积和皮质厚度上.
患有多动症的男性儿童的微观结构性大脑变化需要进一步调查.

研究的目的:

用灰白质对比度 (GWC) 衡量ADHD男性儿童皮质微观结构的变化.
探索GWC和ADHD症状严重程度在男孩之间的关系.

主要方法:

对43名患有多动症的男孩和50名年龄相匹配的对照的3DT1MRI序列进行比较分析.
使用灰白物质对比度 (GWC) 来评估灰色物质密度和白物质微观结构.
用freesurfer 7.2.0进行详细的区域分析来划定皮层区域.

主要成果:

与对照人群相比,在ADHD儿童的双边语言,双边岛屿,左横,右副海马和右皮卡林区域观察到高GWC.
在ADHD和对照组之间没有发现皮层厚度的显著差异.
在左横部GWC和ADHD男孩注意力缺失的严重程度之间发现了负相关性.

结论:

该GWC指标提供了对ADHD儿童微观结构性大脑变化的全面评估.
观察到的GWC波动可能作为ADHD男性儿童结构修饰的神经生物标志物.
左横性GWC与注意力不集中之间的反向相关性突出显示了与ADHD神经病理相关的潜在结构/功能异常.

关键词:

注意力缺陷多动性障碍注意力缺陷多动性障碍皮层厚度皮层厚度灰色-白色物质组织的对比度.没有注意力,没有注意力.男孩男孩孩子男孩孩子

更多相关视频

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Using Brain Activation nir-HEG/Q-EEG and Execution Measures CPTs in a ADHD Assessment Protocol

Published on: April 1, 2018

相关概念视频

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Conduct Disorder

Conduct Disorder

Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...