封锁对1型糖尿病儿童的影响:返回社区与HbA1c的降低有关
Benjamin Morat1, Nadine Lucidarme2, Auriane Gibert2
1Service de Pédiatrie-Urgences, AP-HP, Hôpital Louis-Mourier, Colombes, France.
Frontiers in pediatrics
|January 8, 2024
概括
随着COVID-19的封锁,1型糖尿病 (T1D) 的儿童的血糖控制没有显著改变. 恢复社区活动是保护性的,而与疑似COVID-19病例和感知低血糖症的接触影响了血糖控制.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 2020年3月,COVID-19大流行导致法国需要在全国范围内进行封锁.
- 锁定期间突然的生活方式变化可能会扰乱1型糖尿病 (T1D) 的儿科患者的血糖控制.
研究的目的:
- 评估COVID-19封锁对儿童和青少年T1D诊断的血糖控制的影响.
- 为了确定影响在锁定期间血糖控制变化的因素.
主要方法:
- 在两个儿科中心对118名患有T1D的儿童和青少年进行前性研究.
- 隔离期间之前和之后的糖化血红蛋白 (HbA1c) 水平的比较.
- 分析生活方式因素和临床数据,包括与疑似COVID-19病例的接触和低血糖感知.
主要成果:
- 在封锁之前和之后的中位数HbA1c水平没有发现显著差异 (8.37%与8.50%,p=0.391).
- 恢复社区活动成为防止血糖控制恶化的保护因素 (OR 0.31,p=0.045).
- 增加的HbA1c与与COVID-19疑似病例接触有关 (OR 9.07,p=0.006),而减少的HbA1c与感知低血糖症增加相关 (OR 0.19,p=0.006).
结论:
- 在COVID-19封锁期间,儿科T1D患者的血糖控制保持稳定.
- 重新融入社区生活是一个重要的保护因素.
- 感知低血糖和接触潜在的COVID-19病例与血糖控制的变化有关.
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