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Updated: Jul 6, 2025

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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基双甲衍生物强烈抑制人类和老鼠的11β-基类固醇脱酶1:结构-活性关系和分子对接

Hong Wang1,2, Jianmin Sang1, Zhongyao Ji1

  • 1Department of Anaesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Environmental toxicology
|January 8, 2024
PubMed
概括

化双甲基 (BPA) 衍生物,包括化和化化合物,是人类和老鼠中11β-基固醇脱酶1 (11β-HSD1) 酶的强有力的抑制剂. 抑制功效取决于这些BPA衍生物的化学结构.

关键词:
11β-基类固醇脱酶1绑定模式分析 绑定模式分析皮质醇是一种皮质醇.葡萄糖皮质类药物基双醇是一种基双醇.

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