[可能发生自发性细菌腹膜炎的肝硬化患者的预后和死亡风险因素]
1School of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
概括
肝炎患者可能患有自发性细菌周周炎 (SBP),死亡率很高. 管理层应考虑末期肝病模型 (MELD) 评分和前素水平,以改善生存结果.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 自发性细菌性周周炎 (SBP) 是患有炎的肝硬化患者的严重并发症.
- 区分可能的SBP与其他条件对于适当的管理和预后至关重要.
研究的目的:
- 为了评估可能患有SBP的肝硬化患者的生存结果.
- 为了确定与这种患者群体的死亡率相关的风险因素.
主要方法:
- 追溯分析了323名患有风的肝硬化患者.
- 在患有SBP,细菌,可能SBP和没有感染的患者中,90天死亡率的比较.
- 应用考克斯的比例危险模型和倾向性得分匹配 (PSM) 来确定死亡预测因素.
主要成果:
- 可能的SBP与90天死亡率为43.28%相关,明显高于非感染患者 (11.23%).
- 可能的SBP独立预测了90天死亡率 (HR=1.539).
- 末期肝病 (MELD) 升高模型评分 (>15) 和公素水平 (>0.48 ng/mL) 是可能的SBP患者死亡的独立风险因素.
结论:
- 患有可能SBP的肝硬化患者的存活率较低.
- 可能SBP的预后和管理策略应纳入MELD得分和prcalcitonin水平.
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