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电子烟用于戒烟的电子烟.

Nicola Lindson1, Ailsa R Butler1, Hayden McRobbie2

  • 1Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

The Cochrane database of systematic reviews
|January 8, 2024
PubMed
概括
此摘要是机器生成的。

与尼古丁替代疗法 (NRT) 和非尼古丁EC相比,含尼古丁的电子烟 (EC) 显著增加了戒烟率. 虽然通常是安全的,但长期影响需要进一步研究.

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科学领域:

  • 公共卫生 公共卫生
  • 成 药物 药物 药物 药物
  • 呼吸系统医学 呼吸系统医学

背景情况:

  • 电子烟 (EC) 是一种蒸汽装置,可加热电子液体以产生气溶.
  • 吸烟者,医疗保健提供者和监管机构对EC用于戒烟的疗效和安全感兴趣很大.
  • 本综述是活生生的系统综述的更新,该综述检查了戒烟的EC.

研究的目的:

  • 评估EC的安全性,耐受性和有效性,以帮助吸烟者实现长期戒烟.
  • 比较包括非尼古丁EC,其他戒烟疗法和没有治疗.

主要方法:

  • 系统性审查包括随机对照试验 (RCT) 和不受控制的干预研究.
  • 在多个数据库中进行的搜索截至2023年7月.
  • 主要结局:戒烟 (≥6个月),不良事件 (AE) 和严重不良事件 (SAE).

主要成果:

  • 高确定性证据表明,与NRT相比,尼古丁EC增加了戒烟率 (RR 1.59).
  • 中等确定性证据表明,尼古丁EC增加了戒烟率,而非尼古丁EC则增加了戒烟率 (RR 1.46).
  • 尼古丁EC和NRT/非尼古丁EC之间的AEs是相似的;SAEs是罕见的,对组差异的证据不足.

结论:

  • 与NRT和非尼古丁EC相比,尼古丁EC有效提高戒烟率.
  • 在尼古丁EC和比较剂之间没有观察到AEs的显著差异;SAEs很少见.
  • 虽然有希望,但局限性包括研究偏见和短的随访期;持续的研究至关重要.