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Updated: Jul 6, 2025

Surgical Method for Virally Mediated Gene Delivery to the Mouse Inner Ear through the Round Window Membrane
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通过AAV介导的基因疗法恢复了DFNB9聋患者的听力

Jieyu Qi1,2,3, Fangzhi Tan1, Liyan Zhang1

  • 1State Key Laboratory of Digital Medical Engineering, Department of Otolaryngology Head and Neck Surgery, Zhongda Hospital, School of Life Sciences and Technology, School of Medicine, Advanced Institute for Life and Health, Jiangsu Province High-Tech Key Laboratory for Bio-Medical Research, Southeast University, Nanjing, 210096, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|January 8, 2024
PubMed
概括

使用腺相关病毒OTOF的基因治疗成功地恢复了聋子儿童的听力. 这种OTOF基因替代疗法在治疗遗传性聋症方面显示出有前途的安全性和有效性.

关键词:
在 AAV AAV AAV 中.这是一种OTOF基因疗法.生物安全 生物安全临床试验临床试验临床试验临床试验临床试验听力恢复 听力恢复

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